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Bettina Fries, MD
Infectious Diseases
Highlights
Languages
- French
- German
- English
Gender
FemaleAbout Bettina Fries
Academic Title
Professor of Medicine & Microbiology
Publications
- Optimization of experimental conditions for functional in vitro characterization of humanized antibodies specific for staphylococcal enterotoxin B.
MacIntyre JL | Varshney AK | Wang X | Gatto S | Friedman C | Liu Y | Kerns K | Kovalenko O | Adkins K | Zollner R | Fries BC | Byrne FR
International immunopharmacology
2015 Sep - Aging as an emergent factor that contributes to phenotypic variation in Cryptococcus neoformans.
Bouklas T | Fries BC
Fungal genetics and biology : FG & B
2015 May - Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
Dutta K | Varshney AK | Franklin MC | Goger M | Wang X | Fries BC
The Journal of biological chemistry
2015 Mar 13 - Microrheology with optical tweezers: measuring the relative viscosity of solutions 'at a glance'.
Tassieri M | Del Giudice F | Robertson EJ | Jain N | Fries B | Wilson R | Glidle A | Greco F | Netti PA | Maffettone PL | Bicanic T | Cooper JM
Scientific reports
2015 - Aging: an emergent phenotypic trait that contributes to the virulence of Cryptococcus neoformans.
Bouklas T | Fries BC
Future microbiology
2015 - Characterization of the virulence of Cryptococcus neoformans strains in an insect model.
Bouklas T | Diago-Navarro E | Wang X | Fenster M | Fries BC
Virulence
2015 - ALL2, a Homologue of ALL1, Has a Distinct Role in Regulating pH Homeostasis in the Pathogen Cryptococcus neoformans.
Jain N | Bouklas T | Gupta A | Varshney AK | Orner EP | Fries BC
Infection and immunity
2015 - Methamphetamine Alters the Antimicrobial Efficacy of Phagocytic Cells during Methicillin-Resistant Staphylococcus aureus Skin Infection.
Mihu MR | Roman-Sosa J | Varshney AK | Eugenin EA | Shah BP | Ham Lee H | Nguyen LN | Guimaraes AJ | Fries BC | Nosanchuk JD | Martinez LR
mBio
2015 - Carbapenem-resistant Klebsiella pneumoniae exhibit variability in capsular polysaccharide and capsule associated virulence traits.
Diago-Navarro E | Chen L | Passet V | Burack S | Ulacia-Hernando A | Kodiyanplakkal RP | Levi MH | Brisse S | Kreiswirth BN | Fries BC
The Journal of infectious diseases
2014 Sep 1 - Humanized staphylococcal enterotoxin B (SEB)-specific monoclonal antibodies protect from SEB intoxication and Staphylococcus aureus infections alone or as adjunctive therapy with vancomycin.
Varshney AK | Wang X | MacIntyre J | Zollner RS | Kelleher K | Kovalenko OV | Pechuan X | Byrne FR | Fries BC
The Journal of infectious diseases
2014 Sep 15 - Detection and measurement of staphylococcal enterotoxin-like K (SEl-K) secretion by Staphylococcus aureus clinical isolates.
Aguilar JL | Varshney AK | Wang X | Stanford L | Scharff M | Fries BC
Journal of clinical microbiology
2014 Jul - Isotype switching increases efficacy of antibody protection against staphylococcal enterotoxin B-induced lethal shock and Staphylococcus aureus sepsis in mice.
Varshney AK | Wang X | Aguilar JL | Scharff MD | Fries BC
mBio
2014 - Cryptococcus neoformans ex vivo capsule size is associated with intracranial pressure and host immune response in HIV-associated cryptococcal meningitis.
Robertson EJ | Najjuka G | Rolfes MA | Akampurira A | Jain N | Anantharanjit J | von Hohenberg M | Tassieri M | Carlsson A | Meya DB | Harrison TS | Fries BC | Boulware DR | Bicanic T
The Journal of infectious diseases
2014 Jan 1 - Old Cryptococcus neoformans cells contribute to virulence in chronic cryptococcosis.
Bouklas T | Pechuan X | Goldman DL | Edelman B | Bergman A | Fries BC
mBio
2013 - Cryptococcus neoformans constitutes an ideal model organism to unravel the contribution of cellular aging to the virulence of chronic infections.
Bouklas T | Fries BC
Current opinion in microbiology
2013 Aug - Allergen1 regulates polysaccharide structure in Cryptococcus neoformans.
Jain N | Cordero RJ | Casadevall A | Fries BC
Molecular microbiology
2013 May - Bacterial Toxins-Staphylococcal Enterotoxin B.
Fries BC | Varshney AK
Microbiology spectrum
2013 Dec - Staphylococcal Enterotoxin B-specific monoclonal antibody 20B1 successfully treats diverse Staphylococcus aureus infections.
Varshney AK | Wang X | Scharff MD | MacIntyre J | Zollner RS | Kovalenko OV | Martinez LR | Byrne FR | Fries BC
The Journal of infectious diseases
2013 Dec 15 - Diagnosis and inflammatory response of patients with candiduria.
Helbig S | Achkar JM | Jain N | Wang X | Gialanella P | Levi M | Fries BC
Mycoses
2013 Jan - Methicillin-susceptible Staphylococcus aureus ST398, New York and New Jersey, USA.
Mediavilla JR | Chen L | Uhlemann AC | Hanson BM | Rosenthal M | Stanak K | Koll B | Fries BC | Armellino D | Schilling ME | Weiss D | Smith TC | Lowy FD | Kreiswirth BN
Emerging infectious diseases
2012 Apr - Optimal irrigation and debridement of infected joint implants: an in vitro methicillin-resistant Staphylococcus aureus biofilm model.
Schwechter EM | Folk D | Varshney AK | Fries BC | Kim SJ | Hirsh DM
The Journal of arthroplasty
2011 Sep - Frequency of panton-valentine leukocidin-producing methicillin-sensitive Staphylococcus strains in patients with complicated skin and soft tissue infection in bronx, new york.
Kaltsas A | Guh A | Mediavilla JR | Varshney AK | Robiou N | Gialanellia P | Henry M | Levi MH | Fries BC
Journal of clinical microbiology
2011 Aug - Generation, characterization, and epitope mapping of neutralizing and protective monoclonal antibodies against staphylococcal enterotoxin B-induced lethal shock.
Varshney AK | Wang X | Cook E | Dutta K | Scharff MD | Goger MJ | Fries BC
The Journal of biological chemistry
2011 Mar 18 - Chronological aging is associated with biophysical and chemical changes in the capsule of Cryptococcus neoformans.
Cordero RJ | Pontes B | Guimaraes AJ | Martinez LR | Rivera J | Fries BC | Nimrichter L | Rodrigues ML | Viana NB | Casadevall A
Infection and immunity
2011 Dec - A murine model for catheter-associated candiduria.
Wang X | Fries BC
Journal of medical microbiology
2011 Oct - Variability of phenotypic traits in Cryptococcus varieties and species and the resulting implications for pathogenesis.
Gupta G | Fries BC
Future microbiology
2010 May - Candida infections of the genitourinary tract.
Achkar JM | Fries BC
Clinical microbiology reviews
2010 Apr - Cryptococcus neoformans variants generated by phenotypic switching differ in virulence through effects on macrophage activation.
Guerrero A | Jain N | Wang X | Fries BC
Infection and immunity
2010 Mar - Fungal Biofilms: Relevance in the Setting of Human Disease.
Martinez LR | Fries BC
Current fungal infection reports
2010 Dec 1 - Augmented production of Panton-Valentine leukocidin toxin in methicillin-resistant and methicillin-susceptible Staphylococcus aureus is associated with worse outcome in a murine skin infection model.
Varshney AK | Martinez LR | Hamilton SM | Bryant AE | Levi MH | Gialanella P | Stevens DL | Fries BC
The Journal of infectious diseases
2010 Jan 1 - Biofilm formation in clinical Candida isolates and its association with virulence.
Hasan F | Xess I | Wang X | Jain N | Fries BC
Microbes and infection / Institut Pasteur
2009 Jul-Aug - Isolation and characterization of senescent Cryptococcus neoformans and implications for phenotypic switching and pathogenesis in chronic cryptococcosis.
Jain N | Cook E | Xess I | Hasan F | Fries D | Fries BC
Eukaryotic cell
2009 Jun - Climate change and infectious disease.
Fries BC | Mayer J
Interdisciplinary perspectives on infectious diseases
2009 - Antigenic and phenotypic variations in fungi.
Jain N | Fries BC
Cellular microbiology
2009 Dec - Diverse enterotoxin gene profiles among clonal complexes of Staphylococcus aureus isolates from the Bronx, New York.
Varshney AK | Mediavilla JR | Robiou N | Guh A | Wang X | Gialanella P | Levi MH | Kreiswirth BN | Fries BC
Applied and environmental microbiology
2009 Nov - Loss of allergen 1 confers a hypervirulent phenotype that resembles mucoid switch variants of Cryptococcus neoformans.
Jain N | Li L | Hsueh YP | Guerrero A | Heitman J | Goldman DL | Fries BC
Infection and immunity
2009 Jan - Phenotypic Switching in Fungi.
Jain N | Hasan F | Fries BC
Current fungal infection reports
2008 Sep 1 - Phenotypic switching in Cryptococcus neoformans contributes to virulence by changing the immunological host response.
Guerrero A | Fries BC
Infection and immunity
2008 Sep - Phenotypic switching of Cryptococcus neoformans and Cryptococcus gattii.
Jain N | Fries BC
Mycopathologia
2008 Oct - Characterization of phenotypic switching in Cryptococcus neoformans biofilms.
Martinez LR | Ibom DC | Casadevall A | Fries BC
Mycopathologia
2008 Oct - Measurement of staphylococcal enterotoxin B in serum and culture supernatant with a capture enzyme-linked immunosorbent assay.
Cook E | Wang X | Robiou N | Fries BC
Clinical and vaccine immunology : CVI
2007 Sep - Capsule structural heterogeneity and antigenic variation in Cryptococcus neoformans.
McFadden DC | Fries BC | Wang F | Casadevall A
Eukaryotic cell
2007 Aug - Biofilm formation by and antifungal susceptibility of Candida isolates from urine.
Jain N | Kohli R | Cook E | Gialanella P | Chang T | Fries BC
Applied and environmental microbiology
2007 Mar - Subcutaneous cryptococcosis due to Cryptococcus diffluens in a patient with sporotrichoid lesions case report, features of the case isolate and in vitro antifungal susceptibilities.
Kantarcioglu AS | Boekhout T | De Hoog GS | Theelen B | Yucel A | Ekmekci TR | Fries BC | Ikeda R | Koslu A | Altas K
Medical mycology
2007 Mar - Phagocytic efficacy of macrophage-like cells as a function of cell cycle and Fcgamma receptors (FcgammaR) and complement receptor (CR)3 expression.
Luo Y | Cook E | Fries BC | Casadevall A
Clinical and experimental immunology
2006 Aug - Phenotypic switching and its implications for the pathogenesis of Cryptococcus neoformans.
Jain N | Guerrero A | Fries BC
FEMS yeast research
2006 Jun - Phenotypic switching in a Cryptococcus neoformans variety gattii strain is associated with changes in virulence and promotes dissemination to the central nervous system.
Jain N | Li L | McFadden DC | Banarjee U | Wang X | Cook E | Fries BC
Infection and immunity
2006 Feb - Characterization of a flocculation-like phenotype in Cryptococcus neoformans and its effects on pathogenesis.
Li L | Zaragoza O | Casadevall A | Fries BC
Cellular microbiology
2006 Nov - Phenotypic switching in Cryptococcus neoformans.
Guerrero A | Jain N | Goldman DL | Fries BC
Microbiology (Reading, England)
2006 Jan - Phenotypic switching of Cryptococcus neoformans can produce variants that elicit increased intracranial pressure in a rat model of cryptococcal meningoencephalitis.
Fries BC | Lee SC | Kennan R | Zhao W | Casadevall A | Goldman DL
Infection and immunity
2005 Mar - Cytomegalovirus disease before hematopoietic cell transplantation as a risk for complications after transplantation.
Fries BC | Riddell SR | Kim HW | Corey L | Dahlgren C | Woolfrey A | Boeckh M
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
2005 Feb - Molecular epidemiology of clinical Cryptococcus neoformans strains from India.
Jain N | Wickes BL | Keller SM | Fu J | Casadevall A | Jain P | Ragan MA | Banerjee U | Fries BC
Journal of clinical microbiology
2005 Nov - Effects of antifungal interventions on the outcome of experimental infections with phenotypic switch variants of Cryptococcus neoformans.
Fries BC | Cook E | Wang X | Casadevall A
Antimicrobial agents and chemotherapy
2005 Jan - Recent advances in the prevention of CMV infection and disease after hematopoietic stem cell transplantation.
Boeckh M | Fries B | Nichols WG
Pediatric transplantation
2004 Jun - Phenotypic switching of Cryptococcus neoformans can influence the outcome of the human immune response.
Pietrella D | Fries B | Lupo P | Bistoni F | Casadevall A | Vecchiarelli A
Cellular microbiology
2003 Aug - Induction of capsule growth in Cryptococcus neoformans by mammalian serum and CO(2).
Zaragoza O | Fries BC | Casadevall A
Infection and immunity
2003 Nov - Phenotypic switching in Cryptococcus neoformans.
Fries BC | Goldman DL | Casadevall A
Microbes and infection / Institut Pasteur
2002 Nov - Phenotypic switching of Cryptococcus neoformans occurs in vivo and influences the outcome of infection.
Fries BC | Taborda CP | Serfass E | Casadevall A
The Journal of clinical investigation
2001 Dec - Evidence of zoonotic transmission of Cryptococcus neoformans from a pet cockatoo to an immunocompromised patient.
Nosanchuk JD | Shoham S | Fries BC | Shapiro DS | Levitz SM | Casadevall A
Annals of internal medicine
2000 Feb 1 - Fungal morphogenesis and virulence.
San-Blas G | Travassos LR | Fries BC | Goldman DL | Casadevall A | Carmona AK | Barros TF | Puccia R | Hostetter MK | Shanks SG | Copping VM | Knox Y | Gow NA
Medical mycology
2000 - Phenotypic switching in Cryptococcus neoformans results in changes in cellular morphology and glucuronoxylomannan structure.
Fries BC | Goldman DL | Cherniak R | Ju R | Casadevall A
Infection and immunity
1999 Nov - Genetic relationship between Cryptococcus neoformans var. neoformans strains of serotypes A and D.
Franzot SP | Fries BC | Cleare W | Casadevall A
Journal of clinical microbiology
1998 Aug - Serial isolates of Cryptococcus neoformans from patients with AIDS differ in virulence for mice.
Fries BC | Casadevall A
The Journal of infectious diseases
1998 Dec - Phenotypic switching in the human pathogenic fungus Cryptococcus neoformans is associated with changes in virulence and pulmonary inflammatory response in rodents.
Goldman DL | Fries BC | Franzot SP | Montella L | Casadevall A
Proceedings of the National Academy of Sciences of the United States of America
1998 Dec 8 - Karyotype instability in Cryptococcus neoformans infection.
Fries BC | Chen F | Currie BP | Casadevall A
Journal of clinical microbiology
1996 Jun - Frequency distribution of cytomegalovirus envelope glycoprotein genotypes in bone marrow transplant recipients.
Fries BC | Chou S | Boeckh M | Torok-Storb B
The Journal of infectious diseases
1994 Apr - Declining lymphocyte counts following cytomegalovirus (CMV) infection are associated with fatal CMV disease in bone marrow transplant patients.
Fries BC | Khaira D | Pepe MS | Torok-Storb B
Experimental hematology
1993 Sep - Cytomegalovirus: variations in tropism and disease.
Torok-Storb B | Fries B | Stachel D | Khaira D
Leukemia
1993 Aug
Expertise
Education
- Fellowship: Montefiore Medical Center, IM-Infect Disease, 1999
- Residency: Montefiore Medical Center, Internal Medicine, 1996
- Research Fellowship: Fred Hutchinson Cancer Research Center, 1993
- Medical School: Albert Ludwig Universitaet Freiburg, 1991
Board Certifications
- Infectious Disease: American Board of Internal Medicine, 2008
- Internal Medicine: American Board of Internal Medicine, 2006
Insurance
Please contact the doctor's office directly to confirm acceptance of insurance.
Search plans
- (Anthem) EMP HEALTH CHOICE HMO
- (Anthem) EMP HEALTH CHOICE MEDICAID
- (Anthem) EMP HEALTH CHOICE PPO
- (Anthem) EMP HEALTH CHOICE SR
- (Emblem) HIP
- AETNA
- Affinity
- Beech Street
- Beech Street/Multiplan/PHCS
- Centerlight (CCM)
- CIGNA HMO
- CIGNA PPO
- Fidelis
- GHI / MEDICARE PLUS
- GHI CBP
- GHI HMO
- Great West
- Health Smart WTC
- HEALTHFIRST
- Humana Military
- MAGNACARE
- MET EMPIRE
- OXFORD
- Partners Health Plan
- Sedgwick
- UNITED HEALTHCARE
- Workers Compensation

